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Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny

Understanding how the strength of an effector T cell response is regulated is a fundamental problem in immunology with implications for immunity to pathogens, autoimmunity, and immunotherapy. The initial magnitude of the T cell response is determined by the sum of independent signals from antigen, c...

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Detalhes bibliográficos
Main Authors: Mark R. Dowling, Andrey Kan, Susanne Heinzel, Julia M. Marchingo, Philip D. Hodgkin, Edwin D. Hawkins
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-10-01
Colecção:Frontiers in Immunology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02461/full
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