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Crystal structure of the functional domain of the splicing factor Prp18

The splicing factor Prp18 is required for the second step of pre-mRNA splicing. We have isolated and determined the crystal structure of a large fragment of the Saccharomyces cerevisiae Prp18 that lacks the N-terminal 79 amino acids. This fragment, called Prp18Δ79, is fully active in yeast splicing...

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Autors principals: Jiang, Jianzhong, Horowitz, David S., Xu, Rui-Ming
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC16185/
https://ncbi.nlm.nih.gov/pubmed/10737784
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