Crystal structure of the functional domain of the splicing factor Prp18
The splicing factor Prp18 is required for the second step of pre-mRNA splicing. We have isolated and determined the crystal structure of a large fragment of the Saccharomyces cerevisiae Prp18 that lacks the N-terminal 79 amino acids. This fragment, called Prp18Δ79, is fully active in yeast splicing...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC16185/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10737784/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.7.3022 |
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