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Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

Several of the inhibitor of apoptosis protein (IAP) family members regulate apoptosis in response to various cellular assaults. Some members are also involved in cell signalling, mitosis and targeting proteins to the ubiquitin-proteasome degradation machinery. The most intensively studied family mem...

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Main Authors: Eckelman, Brendan P, Salvesen, Guy S, Scott, Fiona L
Formato: Artigo
Idioma:Inglês
Publicado: 2006
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618369/
https://ncbi.nlm.nih.gov/pubmed/17016456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.embor.7400795
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