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Zinc Eluted from Siliconized Latex Urinary Catheters Decreases OprD Expression, Causing Carbapenem Resistance in Pseudomonas aeruginosa

The activities of carbapenems against Pseudomonas aeruginosa decreased in the presence of siliconized latex urinary catheters (SLUCs). This effect was associated with the loss of OprD. The zinc that eluted from SLUCs is responsible for this phenomenon. We have found that zinc exerts a negative effec...

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Detalhes bibliográficos
Main Authors: Conejo, M. Carmen, García, Isabel, Martínez-Martínez, Luis, Picabea, Leandro, Pascual, Álvaro
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC161826/
https://ncbi.nlm.nih.gov/pubmed/12821486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.47.7.2313-2315.2003
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