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Regulation of p53 tumour suppressor target gene expression by the p52 NF-κB subunit

The p52/p100 nuclear factor kappa B (NF-κB) subunit (NF-κB2) is aberrantly expressed in many tumour types and has been implicated as a regulator of cell proliferation. Here, we demonstrate that endogenous p52 is a direct regulator of Cyclin D1 expression. However, stimulation of Cyclin D1 expression...

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Detalhes bibliográficos
Main Authors: Schumm, Katie, Rocha, Sonia, Caamano, Jorge, Perkins, Neil D
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618099/
https://ncbi.nlm.nih.gov/pubmed/16990795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601343
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