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Role of conserved intracellular motifs in Serrate signalling, cis-inhibition and endocytosis

Notch is the receptor in a signalling pathway that operates in a diverse spectrum of developmental processes. Its ligands (e.g. Serrate) are transmembrane proteins whose signalling competence is regulated by the endocytosis-promoting E3 ubiquitin ligases, Mindbomb1 and Neuralized. The ligands also i...

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Detalhes bibliográficos
Main Authors: Glittenberg, Marcus, Pitsouli, Chrysoula, Garvey, Clare, Delidakis, Christos, Bray, Sarah
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1618092/
https://ncbi.nlm.nih.gov/pubmed/17006545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601337
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