An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling

Cell-to-cell communication via the Notch pathway is mediated between the membrane-bound Notch receptor and either of its canonical membrane-bound ligands Delta or Serrate. Notch ligands mediate receptor transactivation between cells and also mediate receptor cis-inhibition when Notch and ligand are...

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Main Authors: Fleming, Robert J., Hori, Kazuya, Sen, Anindya, Filloramo, Gina V., Langer, Jillian M., Obar, Robert A., Artavanis-Tsakonas, Spyros, Maharaj-Best, Ayiti C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Company of Biologists 2013
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Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3631976/
https://ncbi.nlm.nih.gov/pubmed/23571220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.087916
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