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Herpes Simplex Virus ICP27 Is Required for Virus-Induced Stabilization of the ARE-Containing IEX-1 mRNA Encoded by the Human IER3 Gene

Herpes simplex virus (HSV) stifles cellular gene expression during productive infection of permissive cells, thereby diminishing host responses to infection. Host shutoff is achieved largely through the complementary actions of two viral proteins, ICP27 and virion host shutoff (vhs), that inhibit ce...

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Detalhes bibliográficos
Main Authors: Corcoran, Jennifer A., Hsu, Wei-Li, Smiley, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617249/
https://ncbi.nlm.nih.gov/pubmed/16973576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01216-06
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