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Proteasome Inhibition Reveals that a Functional Preintegration Complex Intermediate Can Be Generated during Restriction by Diverse TRIM5 Proteins

The primate TRIM5 proteins constitute a class of restriction factors that prevent host cell infection by retroviruses from different species. The TRIM5 proteins act early after virion entry and prevent viral reverse transcription products from accumulating. We recently found that proteasome inhibito...

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Bibliografiske detaljer
Main Authors: Anderson, Jenny L., Campbell, Edward M., Wu, Xiaolu, Vandegraaff, Nick, Engelman, Alan, Hope, Thomas J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617233/
https://ncbi.nlm.nih.gov/pubmed/16973579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01052-06
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