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Inhibition of fatty acid amide hydrolase produces analgesia by multiple mechanisms

1. The reversible fatty acid amide hydrolase (FAAH) inhibitor OL135 reverses mechanical allodynia in the spinal nerve ligation (SNL) and mild thermal injury (MTI) models in the rat. The purpose of this study was to investigate the role of the cannabinoid and opioid systems in mediating this analgesi...

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Detalhes bibliográficos
Main Authors: Chang, Leon, Luo, Lin, Palmer, James A, Sutton, Steven, Wilson, Sandy J, Barbier, Ann J, Breitenbucher, James Guy, Chaplan, Sandra R, Webb, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617043/
https://ncbi.nlm.nih.gov/pubmed/16501580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706699
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