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Inhibition of autophosphorylation of epidermal growth factor receptor by small peptides in vitro

1. Inhibition of uncontrolled epidermal growth factor receptor (EGFR) is one of the approaches for the treatment of breast and lung cancers. We designed oligopeptides consisting of amino-acid sequences of the major (Y1068, Y1148, and Y1173) and minor (Y992) autophosphorylation sites of EGFR. These p...

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Detalhes bibliográficos
Main Authors: Abe, Mineo, Kuroda, Yoshihiro, Hirose, Munetaka, Watanabe, Yoshihiko, Nakano, Minoru, Handa, Tetsurou
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1616988/
https://ncbi.nlm.nih.gov/pubmed/16402038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0706634
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