Depression During Pegylated Interferon-Alpha Plus Ribavirin Therapy: Prevalence and Prediction

BACKGROUND: Interferon-alpha (IFN-alpha) plus ribavirin is used to treat hepatitis C virus (HCV) infection and is associated with a high rate of depression. Newer, pegylated preparations of IFN-alpha have a longer half-life, require once-per-week dosing, and may be associated with reduced neuropsych...

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Main Authors: Raison, Charles L., Borisov, Andrey S., Broadwell, Sherry D., Capuron, Lucile, Woolwine, Bobbi J., Jacobson, Ira M., Nemeroff, Charles B., Miller, Andrew H.
Format: Artigo
Language:Inglês
Published: 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615913/
https://ncbi.nlm.nih.gov/pubmed/15669887
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