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Inhibition of Amyloid A Amyloidogenesis in Vivo and in Tissue Culture by 4-Deoxy Analogues of Peracetylated 2-Acetamido-2-Deoxy-α- and β-d-Glucose : Implications for the Treatment of Various Amyloidoses

Two novel sugars, 2-acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-α- and β-d-xylo-hexopyranoses, have been synthesized and their effects on heparan sulfate biosynthesis using primary mouse hepatocytes in tissue culture have been assessed. At concentrations of 0.1 and 1.0 mmol/L a mixture of both anomers...

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Bibliografski detalji
Glavni autori: Kisilevsky, Robert, Szarek, Walter A., Ancsin, John B., Elimova, Elena, Marone, Sandra, Bhat, Shridhar, Berkin, Ali
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2004
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615784/
https://ncbi.nlm.nih.gov/pubmed/15161647
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