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Inhibition of Amyloid A Amyloidogenesis in Vivo and in Tissue Culture by 4-Deoxy Analogues of Peracetylated 2-Acetamido-2-Deoxy-α- and β-d-Glucose : Implications for the Treatment of Various Amyloidoses
Two novel sugars, 2-acetamido-1,3,6-tri-O-acetyl-2,4-dideoxy-α- and β-d-xylo-hexopyranoses, have been synthesized and their effects on heparan sulfate biosynthesis using primary mouse hepatocytes in tissue culture have been assessed. At concentrations of 0.1 and 1.0 mmol/L a mixture of both anomers...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Investigative Pathology
2004
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1615784/ https://ncbi.nlm.nih.gov/pubmed/15161647 |
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