Clostridium perfringens Enterotoxin Elicits Rapid and Specific Cytolysis of Breast Carcinoma Cells Mediated through Tight Junction Proteins Claudin 3 and 4

Clostridium perfringens enterotoxin (CPE) induces cytolysis very rapidly through binding to its receptors, the tight junction proteins CLDN 3 and 4. In this study, we investigated CLDN 3 and 4 expression in breast cancer and tested the potential of CPE-mediated therapy. CLDN 3 and 4 proteins were de...

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Detalhes bibliográficos
Main Authors: Kominsky, Scott L., Vali, Mustafa, Korz, Dorian, Gabig, Theodore G., Weitzman, Sigmund A., Argani, Pedram, Sukumar, Saraswati
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615652/
https://ncbi.nlm.nih.gov/pubmed/15111309
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