Prevalent Overexpression of Prolyl Isomerase Pin1 in Human Cancers

Phosphorylation of proteins on serine or threonine residues preceding proline (pSer/Thr-Pro) is a major regulatory mechanism in cell proliferation and transformation. Interestingly, the pSer/Thr-Pro motifs in proteins exist in two distinct cis and trans conformations, whose conversion rate is normal...

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Bibliographic Details
Main Authors: Bao, Lere, Kimzey, Amy, Sauter, Guido, Sowadski, Janusz M., Lu, Kun Ping, Wang, Da-Gong
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615639/
https://ncbi.nlm.nih.gov/pubmed/15111319
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