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Enhanced Stem Cell Survival in Familial Adenomatous Polyposis

Individuals with heterozygous germline adenomatous polyposis coli (APC) mutations or familial adenomatous polyposis (FAP) are born with normal appearing colons but later develop hundreds to thousands of polyps. Tumor progression apparently starts after somatic loss of the normal APC allele, but germ...

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Detalhes bibliográficos
Main Authors: Kim, Kyoung-Mee, Calabrese, Peter, Tavaré, Simon, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1615334/
https://ncbi.nlm.nih.gov/pubmed/15039224
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