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Stability of colon stem cell methylation after neo-adjuvant therapy in a patient with attenuated familial adenomatous polyposis

BACKGROUND: Methylation at certain human CpG rich sequences increases with age. The mechanisms underlying such age-related changes are unclear, but methylation may accumulate slowly in a clock-like manner from birth and record lifetime numbers of stem cell divisions. Alternatively, methylation may f...

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Detalhes bibliográficos
Main Authors: Kim, Jung Yeon, Beart, Robert W, Shibata, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1164411/
https://ncbi.nlm.nih.gov/pubmed/15941485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-5-19
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