The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism

Mice deficient in the plasminogen activator inhibitor-1 gene (PAI-1(−/−) mice) are relatively protected from developing pulmonary fibrosis from bleomycin administration. We hypothesized that one of the protective mechanisms may be the ability of the plasminogen system to enhance hepatocyte growth fa...

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Hlavní autoři: Hattori, Noboru, Mizuno, Shinya, Yoshida, Yuka, Chin, Kazuo, Mishima, Michiaki, Sisson, Thomas H., Simon, Richard H., Nakamura, Toshikazu, Miyake, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2004
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614722/
https://ncbi.nlm.nih.gov/pubmed/14982862
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