The Plasminogen Activation System Reduces Fibrosis in the Lung by a Hepatocyte Growth Factor-Dependent Mechanism

Mice deficient in the plasminogen activator inhibitor-1 gene (PAI-1(−/−) mice) are relatively protected from developing pulmonary fibrosis from bleomycin administration. We hypothesized that one of the protective mechanisms may be the ability of the plasminogen system to enhance hepatocyte growth fa...

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Detalhes bibliográficos
Main Authors: Hattori, Noboru, Mizuno, Shinya, Yoshida, Yuka, Chin, Kazuo, Mishima, Michiaki, Sisson, Thomas H., Simon, Richard H., Nakamura, Toshikazu, Miyake, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2004
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1614722/
https://ncbi.nlm.nih.gov/pubmed/14982862
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