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A Saccharomyces cerevisiae Mutant Unable To Convert Glucose to Glucose-6-Phosphate Accumulates Excessive Glucose in the Endoplasmic Reticulum due to Core Oligosaccharide Trimming

d-Glucose is the preferred carbon and energy source for most eukaryotic cells. Immediately following its uptake, glucose is rapidly phosphorylated to glucose-6-phosphate (Glc-6-P). The yeast Saccharomyces cerevisiae has three enzymes (Hxk1p, Hxk2p, and Glk1p) that convert glucose to Glc-6-P. In the...

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Auteurs principaux: Miseta, Attila, Tökés-Füzesi, Margit, Aiello, David P., Bedwell, David M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC161446/
https://ncbi.nlm.nih.gov/pubmed/12796298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.3.534-541.2003
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