Calcineurin Is Essential for Candida albicans Survival in Serum and Virulence

Calcineurin is a calcium-activated protein phosphatase that is the target of the immunosuppressants cyclosporin A and FK506. In T cells, calcineurin controls nuclear import of the NF-AT transcription factor and gene activation. In plants and fungi, calcineurin functions in stress responses (e.g., te...

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Bibliographic Details
Main Authors: Blankenship, Jill R., Wormley, Floyd L., Boyce, Molly K., Schell, Wiley A., Filler, Scott G., Perfect, John R., Heitman, Joseph
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2003
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC161442/
https://ncbi.nlm.nih.gov/pubmed/12796287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.2.3.422-430.2003
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