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Rheumatic fever–associated Streptococcus pyogenes isolates aggregate collagen

Acute rheumatic fever is a serious autoimmune sequel of Streptococcus pyogenes infection. This study shows that serotype M3 and M18 S. pyogenes isolated during outbreaks of rheumatic fever have the unique capability to bind and aggregate human basement membrane collagen type IV. M3 protein is identi...

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Udgivet i:J Clin Invest
Principais autores: Dinkla, Katrin, Rohde, Manfred, Jansen, Wouter T.M., Kaplan, Edward L., Chhatwal, Gursharan S., Talay, Susanne R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2003
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Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC161421/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12813026/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI17247
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