Nalaganje...
A rapid genome-scale response of the transcriptional oscillator to perturbation reveals a period-doubling path to phenotypic change
Perturbation of the gated-synchrony system in yeast with phenelzine, an antidepressant drug used in the treatment of affective disorders in humans, leads to a rapid lengthening in the period of the genome-wide transcriptional oscillation. The effect is a concerted, genome-scale change in expression...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1613231/ https://ncbi.nlm.nih.gov/pubmed/17043222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604860103 |
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