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Structure-guided design of a novel class of benzyl-sulfonate inhibitors for influenza virus neuraminidase
Influenza NA (neuraminidase) is an antiviral target of high pharmaceutical interest because of its essential role in cleaving sialic acid residues from cell surface glycoproteins and facilitating release of virions from infected cells. The present paper describes the use of structural information in...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1609911/ https://ncbi.nlm.nih.gov/pubmed/16776653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060447 |
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