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Transcriptional noise and cellular heterogeneity in mammalian macrophages

Transcriptional noise is known to play a crucial role in heterogeneity in bacteria and yeast. Mammalian macrophages are known to exhibit cell-to-cell variation in their responses to pathogens, but the source of this heterogeneity is not known. We have developed a detailed stochastic model of gene ex...

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Autori principali: Ramsey, S, Ozinsky, A, Clark, A, Smith, K.D, de Atauri, P, Thorsson, V, Orrell, D, Bolouri, H
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1609340/
https://ncbi.nlm.nih.gov/pubmed/16524838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2005.1808
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