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Rapid Development of Salivary Gland Carcinomas upon Conditional Expression of K-ras Driven by the Cytokeratin 5 Promoter

We have used a recently described model in which a ras oncogene is expressed in cytokeratin 5 (K5)-expressing cells on doxycycline administration to explore the effects of this oncogene in salivary glands of adult mice. Inducible expression of a mutated K-ras gene under the control of the K5 promote...

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Autori principali: Raimondi, Ana R., Vitale-Cross, Lynn, Amornphimoltham, Panomwat, Gutkind, J. Silvio, Molinolo, Alfredo
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606594/
https://ncbi.nlm.nih.gov/pubmed/16651631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050847
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