Sarcolemmal Damage in Dystrophin Deficiency Is Modulated by Synergistic Interactions between Mechanical and Oxidative/Nitrosative Stresses

Dystrophin deficiency is the cause of Duchenne muscular dystrophy, but the precise physiological basis for muscle necrosis remains unclear. To determine whether dystrophin-deficient muscles are abnormally susceptible to oxidative and nitric oxide (NO)-driven tissue stress, a hindlimb ischemia/reperf...

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Autores principales: Dudley, Roy W.R., Danialou, Gawiyou, Govindaraju, Karuthapillai, Lands, Larry, Eidelman, David H., Petrof, Basil J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2006
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Original Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606574/
https://ncbi.nlm.nih.gov/pubmed/16565501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050683
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