Trehalose 6,6′-Dimycolate and Lipid in the Pathogenesis of Caseating Granulomas of Tuberculosis in Mice

Trehalose 6,6′-dimycolate (TDM) is the most abundant, most granulomagenic, and most toxic lipid extractable from the surface of virulent Mycobacterium tuberculosis (MTB). We further examined its toxicity, which requires activation by oily surfaces. Injections of MTB and/or TDM into sensitized mice i...

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Bibliografski detalji
Glavni autori: Hunter, Robert L., Olsen, Margaret, Jagannath, Chinnaswamy, Actor, Jeffrey K.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2006
Teme:
Original Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606544/
https://ncbi.nlm.nih.gov/pubmed/16565499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050848
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