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Trehalose 6,6′-dimycolate on the surface of Mycobacterium tuberculosis modulates surface marker expression for antigen presentation and costimulation in murine macrophages

Trehalose 6,6′-dimycolate (TDM) is the most abundant lipid extracted from Mycobacterium tuberculosis (MTB). TDM promotes MTB survival by decreasing phagosomal acidification and phagolysosomal fusion in macrophages. Delipidation of MTB using petroleum ether removes TDM and decreases MTB survival with...

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書誌詳細
主要な著者: Kan-Sutton, Celestine, Jagannath, Chinnaswamy, Hunter, Robert L.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680729/
https://ncbi.nlm.nih.gov/pubmed/19007905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.micinf.2008.10.006
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