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Plectin Regulates the Organization of Glial Fibrillary Acidic Protein in Alexander Disease

Alexander disease (AxD) is a rare but fatal neurological disorder caused by mutations in the astrocyte-specific intermediate filament protein glial fibrillary acidic protein (GFAP). Histologically, AxD is characterized by cytoplasmic inclusion bodies called Rosenthal fibers (RFs), which contain GFAP...

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Detalhes bibliográficos
Main Authors: Tian, Rujin, Gregor, Martin, Wiche, Gerhard, Goldman, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606531/
https://ncbi.nlm.nih.gov/pubmed/16507904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051028
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