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Caspase-Mediated Cleavage of Glial Fibrillary Acidic Protein within Degenerating Astrocytes of the Alzheimer’s Disease Brain

Recent studies demonstrate roles for activation of caspases and cleavage of cellular proteins within neurons of the Alzheimer’s disease (AD) brain. To determine whether a similar role for caspases also occurs within glial cells in AD, we designed a site-directed caspase-cleavage antibody specific to...

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Hlavní autoři: Mouser, Peter E., Head, Elizabeth, Ha, Kwang-Ho, Rohn, Troy T.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606516/
https://ncbi.nlm.nih.gov/pubmed/16507909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050798
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