Lithocholic Acid Feeding Induces Segmental Bile Duct Obstruction and Destructive Cholangitis in Mice

We determined the mechanisms of hepatobiliary injury in the lithocholic acid (LCA)-fed mouse, an increasingly used model of cholestatic liver injury. Swiss albino mice received control diet or 1% (w/w) LCA diet (for 1, 2, and 4 days), followed by assessment of liver morphology and ultrastructure, ti...

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Bibliografiske detaljer
Main Authors: Fickert, Peter, Fuchsbichler, Andrea, Marschall, Hanns-Ulrich, Wagner, Martin, Zollner, Gernot, Krause, Robert, Zatloukal, Kurt, Jaeschke, Hartmut, Denk, Helmut, Trauner, Michael
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2006
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606500/
https://ncbi.nlm.nih.gov/pubmed/16436656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050404
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