Autoamplification of Tumor Necrosis Factor-α : A Potential Mechanism for the Maintenance of Elevated Tumor Necrosis Factor-α in Male but Not Female Obese Mice

Although tumor necrosis factor-α (TNF-α) is elevated in adipose tissue in obesity and may contribute to the cardiovascular and metabolic risks associated with this condition, the mechanisms leading to elevated TNF-α remain elusive. We hypothesized that autoamplification of TNF-α contributes to the m...

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Hlavní autoři: Neels, Jaap G., Pandey, Manjula, Hotamisligil, Gökhan S., Samad, Fahumiya
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2006
Témata:
Original Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606482/
https://ncbi.nlm.nih.gov/pubmed/16436658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.050699
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