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Fragmentation of the Golgi Apparatus Induced by the Overexpression of Wild-Type and Mutant Human Tau Forms in Neurons

Tau is a microtubule-associated protein enriched in the axonal compartment. In several neurodegene-rative diseases including Alzheimer’s disease, hyperphosphorylated tau accumulates in the somatodendritic compartment, self-aggregates, and forms neurofibrillary tangles. A fragmentation of the neurona...

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Detalhes bibliográficos
Main Authors: Liazoghli, Dalinda, Perreault, Sebastien, Micheva, Kristina D., Desjardins, Mylène, Leclerc, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1606403/
https://ncbi.nlm.nih.gov/pubmed/15855649
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