Angiotensin II Activates Matrix Metalloproteinase Type II and Mimics Age-Associated Carotid Arterial Remodeling in Young Rats

Increased angiotensin II (Ang II), matrix metalloproteinase type II (MMP2), and sympathetic activity accompany age-associated arterial remodeling. To analyze this relationship, we infused a low subpressor dose of Ang II into young (8 months old) rats. This increased carotid arterial MMP2 transcripti...

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Main Authors: Wang, Mingyi, Zhang, Jing, Spinetti, Gaia, Jiang, Li-Qun, Monticone, Robert, Zhao, Di, Cheng, Linda, Krawczyk, Melissa, Talan, Mark, Pintus, Gianfranco, Lakatta, Edward G.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2005
Fag:
Original Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603787/
https://ncbi.nlm.nih.gov/pubmed/16251426
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