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Chronic Matrix Metalloproteinase Inhibition Retards Age-associated Arterial Proinflammation and Increase in Blood Pressure

Age-associated arterial remodeling involves arterial wall collagen deposition and elastin fragmentation, and an increase in arterial pressure. This arterial remodeling is linked to proinflammatory signaling, including transforming growth factor-beta1 (TGF-β1), monocyte chemoattractant protein-1 (MCP...

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Detalhes bibliográficos
Main Authors: Wang, Mingyi, Zhang, Jing, Telljohann, Richard, Jiang, Liqun, Wu, James, Monticone, Robert E., Kapoor, Kapil, Talan, Mark, Lakatta, Edward G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3537179/
https://ncbi.nlm.nih.gov/pubmed/22689745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.112.191270
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