Glomerular Aging in Females Is a Multi-Stage Reversible Process Mediated by Phenotypic Changes in Progenitors

The glomeruli of postmenopausal C57BL6 mice, and age-matched males, show progressive hypertrophy and glomerulosclerosis. We asked whether this was a multistage process, was due to alterations in glomerular progenitors, and was reversible in female mice. Using cross bone marrow transplants (BMT) betw...

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Autori principali: Feng, Zheng, Plati, Anna Rita, Cheng, Qing-li, Berho, Mariana, Banerjee, Anita, Potier, Mylene, Jy, Wen-che, Koff, Andrew, Striker, Liliane J., Striker, Gary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2005
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Original Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1603557/
https://ncbi.nlm.nih.gov/pubmed/16049323
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