Interleukin-6 Gene Ablation in a Transgenic Mouse Model of Malignant Skin Melanoma

Interleukin (IL)-6 is a pleiotropic cytokine that has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro. In patients with metastasizing melanomas, highly increased IL-6 blood levels correlate with a poor response to chemotherap...

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Autors principals: von Felbert, Verena, Córdoba, Francisco, Weissenberger, Jakob, Vallan, Claudio, Kato, Masashi, Nakashima, Izumi, Braathen, Lasse Roger, Weis, Joachim
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2005
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Original Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602365/
https://ncbi.nlm.nih.gov/pubmed/15743795
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