Interleukin-6 Gene Ablation in a Transgenic Mouse Model of Malignant Skin Melanoma

Interleukin (IL)-6 is a pleiotropic cytokine that has been shown to inhibit the growth of early stage and to promote the proliferation of advanced stage melanoma cells in vitro. In patients with metastasizing melanomas, highly increased IL-6 blood levels correlate with a poor response to chemotherap...

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Detalhes bibliográficos
Main Authors: von Felbert, Verena, Córdoba, Francisco, Weissenberger, Jakob, Vallan, Claudio, Kato, Masashi, Nakashima, Izumi, Braathen, Lasse Roger, Weis, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Original Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602365/
https://ncbi.nlm.nih.gov/pubmed/15743795
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