Oxidative Stress in Transgenic Mice with Oligodendroglial α-Synuclein Overexpression Replicates the Characteristic Neuropathology of Multiple System Atrophy

Multiple system atrophy (MSA) is a progressive neurodegenerative disorder characterized by parkinsonism unresponsive to dopaminergic therapy, cerebellar ataxia, and dysautonomia. Neuropathology shows a characteristic neuronal multisystem degeneration that is associated with widespread oligodendrogli...

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Autores principales: Stefanova, Nadia, Reindl, Markus, Neumann, Manuela, Haass, Christian, Poewe, Werner, Kahle, Philipp J., Wenning, Gregor K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2005
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Original Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602361/
https://ncbi.nlm.nih.gov/pubmed/15743798
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