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Matricellular Homologs in the Foreign Body Response: Hevin Suppresses Inflammation, but Hevin and SPARC Together Diminish Angiogenesis

Implanted foreign materials, used to restore or assist tissue function, elicit an initial acute inflammatory response followed by chronic fibrosis that leads to the entrapment of the biomaterial in a thick, poorly vascularized collagenous capsule. Matricellular proteins, secreted macromolecules that...

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Detalhes bibliográficos
Main Authors: Barker, Thomas H., Framson, Paul, Puolakkainen, Pauli A., Reed, May, Funk, Sarah E., Sage, E. Helene
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602349/
https://ncbi.nlm.nih.gov/pubmed/15743803
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