Brain and Bone Damage in KARAP/DAP12 Loss-of-Function Mice Correlate with Alterations in Microglia and Osteoclast Lineages

Human polycystic lipomembraneous osteodysplasia with sclerosing leukoencephalopathy, also known as Nasu-Hakola disease, has been described to be associated with mutations affecting the immunoreceptor tyrosine-based activation motif-bearing KARAP/DAP12 immunoreceptor gene. Patients present bone fragi...

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Autori principali: Nataf, Serge, Anginot, Adrienne, Vuaillat, Carine, Malaval, Luc, Fodil, Nassima, Chereul¶, Emmanuel, Langlois¶, Jean-Baptiste, Dumontel, Christiane, Cavillon, Gaelle, Confavreux, Christian, Mazzorana, Marlène, Vico, Laurence, Belin, Marie-Franaçoise, Vivier, Eric, Tomasello, Elena, Jurdic, Pierre
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2005
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Original Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602283/
https://ncbi.nlm.nih.gov/pubmed/15632019
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