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Toll-Like Receptor 2-Deficient Mice Succumb to Mycobacterium tuberculosis Infection

Recognition of Mycobacterium tuberculosis by the innate immune system is essential in the development of an adaptive immune response. Mycobacterial cell wall components activate macrophages through Toll-like receptor (TLR) 2, suggesting that this innate immune receptor plays a role in the host respo...

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Autors principals: Drennan, Michael B., Nicolle, Delphine, Quesniaux, Valerie J. F., Jacobs, Muazzam, Allie, Nasiema, Mpagi, Joseph, Frémond, Cécile, Wagner, Hermann, Kirschning, Carsten, Ryffel, Bernhard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602241/
https://ncbi.nlm.nih.gov/pubmed/14695318
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