Toll-Like Receptor 2-Deficient Mice Succumb to Mycobacterium tuberculosis Infection

Recognition of Mycobacterium tuberculosis by the innate immune system is essential in the development of an adaptive immune response. Mycobacterial cell wall components activate macrophages through Toll-like receptor (TLR) 2, suggesting that this innate immune receptor plays a role in the host respo...

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Hauptverfasser: Drennan, Michael B., Nicolle, Delphine, Quesniaux, Valerie J. F., Jacobs, Muazzam, Allie, Nasiema, Mpagi, Joseph, Frémond, Cécile, Wagner, Hermann, Kirschning, Carsten, Ryffel, Bernhard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2004
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602241/
https://ncbi.nlm.nih.gov/pubmed/14695318
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