Cysteine 10 Is a Key Residue in Amyloidogenesis of Human Transthyretin Val30Met

Type I familial amyloidotic polyneuropathy (FAP), a systemic amyloidosis, is characterized by aggregation of variant transthyretin (TTR Val30Met) into stable, insoluble fibrils. This aggregation is caused by genetic and environmental factors. Genetic factors have been studied extensively. However, l...

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Bibliografische gegevens
Hoofdauteurs: Takaoka, Yutaka, Ohta, Mika, Miyakawa, Kazuhisa, Nakamura, Osamu, Suzuki, Misao, Takahashi, Kiyoshi, Yamamura, Ken-ichi, Sakaki, Yoshiyuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2004
Onderwerpen:
Animal Model
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602210/
https://ncbi.nlm.nih.gov/pubmed/14695346
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