Mutator Phenotype of Caenorhabditis elegans DNA Damage Checkpoint Mutants

DNA damage response proteins identify sites of DNA damage and signal to downstream effectors that orchestrate either apoptosis or arrest of the cell cycle and DNA repair. The C. elegans DNA damage response mutants mrt-2, hus-1, and clk-2(mn159) displayed 8- to 15-fold increases in the frequency of s...

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Bibliografiske detaljer
Main Authors: Harris, Jasper, Lowden, Mia, Clejan, Iuval, Tzoneva, Monika, Thomas, James H., Hodgkin, Jonathan, Ahmed, Shawn
Format: Artigo
Sprog:Inglês
Udgivet: Copyright © 2006 by the Genetics Society of America 2006
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Investigations
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1602097/
https://ncbi.nlm.nih.gov/pubmed/16951081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.058701
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