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Mutator Phenotype of Caenorhabditis elegans DNA Damage Checkpoint Mutants
DNA damage response proteins identify sites of DNA damage and signal to downstream effectors that orchestrate either apoptosis or arrest of the cell cycle and DNA repair. The C. elegans DNA damage response mutants mrt-2, hus-1, and clk-2(mn159) displayed 8- to 15-fold increases in the frequency of s...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Copyright © 2006 by the Genetics Society of America
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1602097/ https://ncbi.nlm.nih.gov/pubmed/16951081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.058701 |
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