Induction of the Tumor-Suppressor p16(INK4a) within Regenerative Epithelial Crypts in Ulcerative Colitis

p16(INK4a) is a major tumor-suppressor protein, but its regulation and settings of fuction remain poorly understood. To explore the notion that p16 is induced in vivo in response to replicative stress, we examined p16 expression in tissues from human ulcerative colitis (UC; n = 25) and normal contro...

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Autori principali: Furth, Emma E, Gustafson, Karen S, Dai, Charlotte Y, Gibson, Steven L, Menard-Katcher, Paul, Chen, Tina, Koh, Jim, Enders, Greg H
Natura: Artigo
Lingua:Inglês
Pubblicazione: Neoplasia Press Inc. 2006
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Brief Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1601464/
https://ncbi.nlm.nih.gov/pubmed/16820088
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